1,2-Naphthoquinone

1,2-Naphthoquinone
Names
Other names
o-Naphthoquinone,
β-naphthoquinone
Identifiers
524-42-5 YesY
ChEMBL ChEMBL52347 YesY
ChemSpider 10217 YesY
Jmol interactive 3D Image
KEGG C14783 YesY
PubChem 10667
Properties
C10H6O2
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
YesY verify (what is YesYN ?)
Infobox references

1,2-Naphthoquinone or ortho-naphthoquinone is a polycyclic aromatic organic compound with formula C
10
H
6
O
2
.

This double ketone (quinone) is a reactive metabolite of naphthalene and is found in diesel exhaust particles. The accumulation of this toxic metabolite in rats from doses of naphthalene has been shown to cause eye damage, including the formation of cataracts.[1]

See also

References

  1. Qian, W.; Shichi, H. (2001). "Naphthoquinone-Induced Cataract in Mice: Possible Involvement of Ca2+ Release and Calpain Activation". Journal of Ocular Pharmacology and Therapeutics 17 (4): 383–392. doi:10.1089/108076801753162799. PMID 11572469.

External links


This article is issued from Wikipedia - version of the Wednesday, April 29, 2015. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.