1-Pyrroline dehydrogenase

1-pyrroline dehydrogenase
Identifiers
EC number	1.5.1.35
CAS number	9054-82-4
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

1-pyrroline dehydrogenase (EC 1.5.1.35, gamma-aminobutyraldehyde dehydrogenase, ABALDH, YdcW) is an enzyme with systematic name 1-pyrroline:NAD⁺ oxidoreductase.^[1][2][3] This enzyme catalyses the following chemical reaction

1-pyrroline + NAD⁺ + 2 H₂O $\rightleftharpoons$ 4-aminobutanoate + NADH + 2 H⁺

This enzyme participates in the arginine-catabolism pathway.

References

1. Prieto-Santos, M.I., Martin-Checa, J., Balaña-Fouce, R. and Garrido-Pertierra, A. (1986). "A pathway for putrescine catabolism in Escherichia coli". Biochim. Biophys. Acta 880 (2-3): 242–244. doi:10.1016/0304-4165(86)90085-1. PMID 3510672.
2. Prieto, M.I., Martin, J., Balaña-Fouce, R. and Garrido-Pertierra, A. (1987). "Properties of γ-aminobutyraldehyde dehydrogenase from Escherichia coli". Biochimie 69: 1161–1168. doi:10.1016/0300-9084(87)90142-8. PMID 3129020.
3. Samsonova, N.N., Smirnov, S.V., Novikova, A.E. and Ptitsyn, L.R. (2005). "Identification of Escherichia coli K12 YdcW protein as a γ-aminobutyraldehyde dehydrogenase". FEBS Lett. 579: 4107–4112. doi:10.1016/j.febslet.2005.06.038. PMID 16023116.

External links

• 1-pyrroline dehydrogenase at the US National Library of Medicine Medical Subject Headings (MeSH)