3-Methoxymorphinan

Not to be confused with Dextrorphan, Dextromethorphan, or Levomethorphan.
3-Methoxymorphinan
Clinical data
Legal status
Legal status
  • US: unregulated
Identifiers
CAS Number 1531-25-5 N
PubChem CID 5484286
ChemSpider 10207434 YesY
Chemical data
Formula C17H23NO
Molar mass 257.37 g/mol
 NYesY (what is this?)  (verify)

3-Methoxymorphinan is a dextromethorphan metabolite that has been shown to produce local anesthetic effects.[1] It is metabolized in the liver by the enzyme CYP3A4.[2]

See Also

Dextrorphan | Dextromethorphan | Levomethorphan | Morphinan

References

  1. ↑ Hou, Chia-Hui; Tzeng, Jann-Inn; Chen, Yu-Wen; Lin, Ching-Nan; Lin, Mao-Tsun; Tu, Chieh-Hsien; Wang, Jhi-Joung (2006). "Dextromethorphan, 3-methoxymorphinan, and dextrorphan have local anaesthetic effect on sciatic nerve blockade in rats". European Journal of Pharmacology 544 (1–3): 10–6. doi:10.1016/j.ejphar.2006.06.013. PMID 16844109.
  2. ↑ Min, David I.; Ku, Yi-Min; Vichiendilokkul, Aungkana; Fleckenstein, Lawrence L. (1999). "A Urine Metabolic Ratio of Dextromethorphan and 3-Methoxymorphinan as a Probe for CYP3A Activity and Prediction of Cyclosporine Clearance in Healthy Volunteers". Pharmacotherapy 19 (6): 753–9. doi:10.1592/phco.19.9.753.31536. PMID 10391422.
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