3-Hydroxypicolinic acid

3-Hydroxypicolinic acid

Names
IUPAC name 3-hydroxypyridine-2-carboxylic acid
Other names 3-hydroxypyridine-2-carboxylic acid; 2-pyridinecarboxylic acid, 3-hydroxy-; 3-hydroxy-2-pyridinecarboxylic acid
Identifiers
CAS Number	874-24-8
ChEBI	CHEBI:63432
ChemSpider	12827
Jmol interactive 3D	Image Image
PubChem	13401
InChI InChI=1S/C6H5NO3/c8-4-2-1-3-7-5(4)6(9)10/h1-3,8H,(H,9,10) Key: BRARRAHGNDUELT-UHFFFAOYSA-N InChI=1/C6H5NO3/c8-4-2-1-3-7-5(4)6(9)10/h1-3,8H,(H,9,10) Key: BRARRAHGNDUELT-UHFFFAOYAC
SMILES C1=CC(=C(N=C1)C(=O)O)O c1cc(c(nc1)C(=O)O)O
Properties
Chemical formula	C6H5NO3
Molar mass	139.109
Appearance	Light yellow needles
Melting point	208 to 212 °C (406 to 414 °F; 481 to 485 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

3-Hydroxy picolinic acid is a picolinic acid derivative and is a member of the pyridine family. It is used as a matrix for nucleotides in MALDI mass spectrometry analyses.^[1]

See also

• Matrix-assisted laser desorption/ionization
• Sinapinic acid
• Picolinic acid
• α-Cyano-4-hydroxycinnamic acid

References

1. Wu KJ, Steding A, Becker CH (1993). "Matrix-assisted laser desorption time-of-flight mass spectrometry of oligonucleotides using 3-hydroxypicolinic acid as an ultraviolet-sensitive matrix". Rapid Commun. Mass Spectrom. 7 (2): 142–6. doi:10.1002/rcm.1290070206. PMID 8457722.