4-PPBP

4-PPBP
Names


IUPAC name 4-phenyl-1-(4-phenylbutyl) piperidine
Identifiers
CAS Number	136534-70-8^N
ChEMBL	ChEMBL325238^Y
ChemSpider	2299855^Y
Jmol interactive 3D	Image Image
MeSH	4-phenyl-1-(4-phenylbutyl)piperidine
PubChem	3035672
InChI InChI=1S/C21H27N/c1-3-9-19(10-4-1)11-7-8-16-22-17-14-21(15-18-22)20-12-5-2-6-13-20/h1-6,9-10,12-13,21H,7-8,11,14-18H2^Y Key: HQGDPZPNAXRCSA-UHFFFAOYSA-N^Y InChI=1/C21H27N/c1-3-9-19(10-4-1)11-7-8-16-22-17-14-21(15-18-22)20-12-5-2-6-13-20/h1-6,9-10,12-13,21H,7-8,11,14-18H2 Key: HQGDPZPNAXRCSA-UHFFFAOYAV
SMILES C1CN(CCC1C2=CC=CC=C2)CCCCC3=CC=CC=C3 c1ccccc1C3CCN(CCCCc2ccccc2)CC3
Properties
Chemical formula	C₂₁H₂₇N
Molar mass	293.446 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is ^YN ?)
Infobox references

4-PPBP is a molecule which binds to sigma receptors.^[1]

References

↑ Yang S, Bhardwaj A, Cheng J, Alkayed NJ, Hurn PD, Kirsch JR (2007). "Sigma receptor agonists provide neuroprotection in vitro by preserving bcl-2". Anesth. Analg. 104 (5): 1179–84, tables of contents. doi:10.1213/01.ane.0000260267.71185.73. PMC 2596726. PMID 17456670.

Sigma receptor modulators

Receptor
(ligands)

σ (1, 2)

Agonists	3-MeO-PCE 3-MeO-PCP 3-PPP 4-MeO-PCP 4-IBP 4-PPBP Afobazole Alazocine Amitriptyline Arketamine BD-1008 BD1031 BD1052 Berberine Buprenorphine Captodiame Citalopram Clorgiline Cocaine Cutamesine Cyclazocine DHEA DHEA-S Desipramine Dextrallorphan Dextromethorphan Dextrorphan Dimemorfan DMT DTG Escitalopram Fluoxetine Fluvoxamine Heroin Ibogaine Igmesine Imipramine JO-1784 Ketamine L-687,384 Lamotrigine Lu 28-179 MDMA Metaphit Methamphetamine Methoxetamine Methylphenidate Morphine Naluzotan Noscapine OPC-14523 Opipramol PB-28 PD-144,415 Pentazocine Pentoxyverine Phencyclidine PRE-084 Pregnenolone Pregnenolone sulfate Quetiapine RTI-55 SA-4503 Siramesine Tapentadol Tenocyclidine Tramadol UMB23 UMB82 Venlafaxine

Antagonists	AC927 AHD1 AZ66 BD1008 BD-1047 BD1060 BD1063 BD1067 BMY-14802 CM156 E-5842 Haloperidol Lamotrigine LR132 LR172 Memantine MIN-101 MS-377 NE-100 Panamesine PD-144418 Progesterone Rimcazole S1RA (E-52862) Sertraline SM-21 SR-31742A UMB100 UMB101 UMB103 UMB116 YZ-011 YZ-069 YZ-185

Unknown/unsorted	4C-T-2 5-MeO-DiPT 18-MC β-Endopsychosin Clocapramine DiPT DPT Gevotroline TMA; Allosteric modulators: SKF-83959

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