4-Hydroxycoumarin synthase

4-hydroxycoumarin synthase
Identifiers
EC number 2.3.1.208
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

4-hydroxycoumarin synthase (EC 2.3.1.208, BIS2, BIS3) is an enzyme with systematic name malonyl-CoA:2-hydroxybenzoyl-CoA malonyltransferase.[1] This enzyme catalyses the following chemical reaction

malonyl-CoA + 2-hydroxybenzoyl-CoA \rightleftharpoons 2 CoA + 4-hydroxycoumarin + CO2

This polyketide synthase can also accept benzoyl-CoA as substrate.

References

  1. Liu, B., Raeth, T., Beuerle, T. and Beerhues, L. (2010). "A novel 4-hydroxycoumarin biosynthetic pathway". Plant Mol. Biol. 72: 17–25. doi:10.1007/s11103-009-9548-0. PMID 19757094.

External links

This article is issued from Wikipedia - version of the Wednesday, March 30, 2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.