4-Hydroxycoumarin synthase
4-hydroxycoumarin synthase | |||||||||
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Identifiers | |||||||||
EC number | 2.3.1.208 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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4-hydroxycoumarin synthase (EC 2.3.1.208, BIS2, BIS3) is an enzyme with systematic name malonyl-CoA:2-hydroxybenzoyl-CoA malonyltransferase.[1] This enzyme catalyses the following chemical reaction
- malonyl-CoA + 2-hydroxybenzoyl-CoA 2 CoA + 4-hydroxycoumarin + CO2
This polyketide synthase can also accept benzoyl-CoA as substrate.
References
- ↑ Liu, B., Raeth, T., Beuerle, T. and Beerhues, L. (2010). "A novel 4-hydroxycoumarin biosynthetic pathway". Plant Mol. Biol. 72: 17–25. doi:10.1007/s11103-009-9548-0. PMID 19757094.
External links
- 4-hydroxycoumarin synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
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