4-Methylaminobutanoate oxidase (formaldehyde-forming)

4-methylaminobutanoate oxidase (formaldehyde-forming) (EC 1.5.3.19, mabO (gene)) is an enzyme with systematic name 4-methylaminobutanoate:oxygen oxidoreductase (formaldehyde-forming).^[1] This enzyme catalyses the following chemical reaction

4-methylaminobutanoate + O₂ + H₂O

\rightleftharpoons

4-aminobutanoate + formaldehyde + H₂O₂

This enzyme is a flavoprotein (FAD).

References

↑ Chiribau, C.B., Sandu, C., Fraaije, M., Schiltz, E. and Brandsch, R. (2004). "A novel γ-N-methylaminobutyrate demethylating oxidase involved in catabolism of the tobacco alkaloid nicotine by Arthrobacter nicotinovorans pAO1". Eur. J. Biochem. 271 (23-24): 4677–4684. doi:10.1111/j.1432-1033.2004.04432.x. PMID 15606755.

External links

4-methylaminobutanoate oxidase (formaldehyde-forming) at the US National Library of Medicine Medical Subject Headings (MeSH)

Oxidoreductases: CH-NH (EC 1.5)

1.5.1: NAD or NADP acceptor	Dihydrofolate reductase Saccharopine dehydrogenase Methylenetetrahydrofolate reductase

1.5.3: oxygen acceptor	Dihydrobenzophenanthridine oxidase Sarcosine oxidase Proline oxidase

1.5.5: quinone acceptor	Electron-transferring-flavoprotein dehydrogenase

1.5.99	Sarcosine dehydrogenase Cytokinin dehydrogenase

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases(list) EC2 Transferases(list) EC3 Hydrolases(list) EC4 Lyases(list) EC5 Isomerases(list) EC6 Ligases(list)

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