5-Formiminotetrahydrofolate

5-Formiminotetrahydrofolate
Skeletal formula of 5-formiminotetrahydrofolate.
Skeletal formula of the 5-formiminotetrahydrofolate molecule
Names
IUPAC name
(2S)-2-{[4-[(2-Amino-5-methanimidoyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino}pentanedioic acid
Identifiers
2311-81-1 N
ChemSpider 21232465 YesY
Jmol interactive 3D Image
PubChem 530
Properties
C20H24N8O6
Molar mass 472.455
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

5-Formiminotetrahydrofolate is an intermediate in the catabolism of histidine. It is produced by glutamate formimidoyltransferase and then converted into 5,10-methenyltetrahydrofolate by formiminotransferase cyclodeaminase.[1]

References

  1. Fowler B (February 2001). "The folate cycle and disease in humans". Kidney Int. Suppl. 78: S221–9. doi:10.1046/j.1523-1755.2001.07851.x. PMID 11169015.


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