8-Hydroxygeraniol

8-Hydroxygeraniol
Names
IUPAC name
(2E,6E)-2,6-Dimethyl-2,6-octadiene-1,8-diol
Identifiers
26488-97-1
ChemSpider 4515751
Jmol interactive 3D Image
PubChem 5363397
Properties
C10H18O2
Molar mass 170.25 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

8-Hydroxygeraniol (also called 10-hydroxygeraniol)[1] is a monoterpene synthesized from geraniol by they enzyme geraniol 8-hydroxylase. 8-Hydroxygeraniol is a substrate for 8-hydroxygeraniol dehydrogenase (G80) which synthesizes 8-oxogeranial.[2] 8-Hydroxygeraniol is step in the synthesis of the secologanin, a key monoterpene needed for formation of terpene indole alkaloids.

References

  1. Dewick (2009) Medicinal Natural Products: A Biosynthetic Approach.
  2. Miettinen, Karel; Dong, Lemeng; Navrot, Nicolas; Schneider, Thomas; Burlat, Vincent; Pollier, Jacob; Woittiez, Lotte; Van Der Krol, Sander; Lugan, Raphaël; Ilc, Tina; Verpoorte, Robert; Oksman-Caldentey, Kirsi-Marja; Martinoia, Enrico; Bouwmeester, Harro; Goossens, Alain; Memelink, Johan; Werck-Reichhart, Danièle (2014). "The seco-iridoid pathway from Catharanthus roseus". Nature Communications 5. Bibcode:2014NatCo...5.....M. doi:10.1038/ncomms4606.
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