A-1 holin family

The Actinobacterial 1 TMS Holin (A-1 Holin) Family (TC# 1.E.32) consists of proteins found in actinobacteria, their conjugative plasmids and their phage.^[1] They are usually between 90 and 140 amino acyl residues (aas) in length and exhibit 1 or sometimes even 2 transmembrane segments despite the families name (i.e., TC# 1.E.32.2.1). Although some are annotated as phage proteins or holins, members of the A-1 family are not yet functionally characterized. A representative list of proteins belonging to the A-1 Holin family can be found in the Transporter Classification Database (TCDB).^[2]

See also

• Holin
• Lysin
• Transporter Classification Database

Further reading

• Wang, I. N.; Smith, D. L.; Young, R. (2000-01-01). "Holins: the protein clocks of bacteriophage infections". Annual Review of Microbiology 54: 799–825.doi:10.1146/annurev.micro.54.1.799. ISSN 0066-4227.PMID 11018145.

References

1. Delisle, Allan L.; Barcak, Gerard J.; Guo, Ming (2006-02-01). "Isolation and expression of the lysis genes of Actinomyces naeslundii phage Av-1". Applied and Environmental Microbiology 72 (2): 1110–1117. doi:10.1128/AEM.72.2.1110-1117.2006. ISSN 0099-2240. PMC 1392916. PMID 16461656.
2. "1.E.32 Actinobacterial 1 TMS Holin (A-1 Holin) Family". TCDB. Retrieved 2016-03-28.

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