Nolatrexed

Nolatrexed
Names
IUPAC name
2-Amino-6-methyl-5-(4-pyridylthio)-1H-quinazolin-4-one
Identifiers
147149-76-6 YesY
ChemSpider 97268 N
Jmol interactive 3D Image
PubChem 108189
UNII K75ZUN743Q YesY
Properties
C14H12N4OS
Molar mass 284.34 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Nolatrexed is a thymidylate synthase inhibitor.[1][2]

References

  1. Hughes AN, Rafi I, Griffin MJ, et al. (January 1999). "Phase I studies with the nonclassical antifolate nolatrexed dihydrochloride (AG337, THYMITAQ) administered orally for 5 days". Clin. Cancer Res. 5 (1): 111–8. PMID 9918208.
  2. "Nolatrexed". PubChem.gov. Pub Chem. Retrieved 12 August 2014.


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