AP1AR

Adaptor-related protein complex 1 associated regulatory protein
Identifiers
Symbols	AP1AR ; 2C18; C4orf16; GBAR; PRO0971; gamma-BAR
External IDs	OMIM: 610851 MGI: 2384822 HomoloGene: 10236 GeneCards: AP1AR Gene
Gene ontology Molecular function • kinesin binding • AP-1 adaptor complex binding Cellular component • early endosome • late endosome • Golgi apparatus • transport vesicle Biological process • negative regulation of receptor recycling • protein transport • regulation of Arp2/3 complex-mediated actin nucleation • cellular protein localization • vesicle targeting, trans-Golgi to endosome • negative regulation of substrate adhesion-dependent cell spreading • negative regulation of cell motility Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	55435	211556
Ensembl	ENSG00000138660	ENSMUSG00000074238
UniProt	Q63HQ0	E9PYF7
RefSeq (mRNA)	NM_001128426	NM_145964
RefSeq (protein)	NP_001121898	NP_666076
Location (UCSC)	Chr 4: 112.23 – 112.27 Mb	Chr 3: 127.81 – 127.84 Mb
PubMed search

AP-1 complex-associated regulatory protein (Gamma1-adaptin brefeldin A resistance protein) is a protein that in humans is encoded by the AP1AR gene.^[1][2]

References

1. Neubrand VE, Will RD, Mobius W, Poustka A, Wiemann S, Schu P, Dotti CG, Pepperkok R, Simpson JC (Apr 2005). "Gamma-BAR, a novel AP-1-interacting protein involved in post-Golgi trafficking". EMBO J 24 (6): 1122–33. doi:10.1038/sj.emboj.7600600. PMC 556403. PMID 15775984.
2. "Entrez Gene: C4orf16 chromosome 4 open reading frame 16".

Further reading

• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Wiemann S, Weil B, Wellenreuther R; et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Simpson JC, Wellenreuther R, Poustka A; et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Brill LM, Salomon AR, Ficarro SB; et al. (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.". Anal. Chem. 76 (10): 2763–72. doi:10.1021/ac035352d. PMID 15144186.
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Wiemann S, Arlt D, Huber W; et al. (2004). "From ORFeome to biology: a functional genomics pipeline.". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Hillier LW, Graves TA, Fulton RS; et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4.". Nature 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.
• Mehrle A, Rosenfelder H, Schupp I; et al. (2006). "The LIFEdb database in 2006.". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.