ARL8A

ADP-ribosylation factor-like 8A
PDB rendering based on 1zd9.
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 1ZD9​, 2H18​, 4ILE​
Identifiers
Symbols	ARL8A ; ARL10B; GIE2
External IDs	MGI: 1915974 HomoloGene: 23600 GeneCards: ARL8A Gene
Gene ontology Molecular function • GTPase activity • protein binding • GTP binding • alpha-tubulin binding • beta-tubulin binding Cellular component • cytoplasm • lysosomal membrane • membrane • midbody • late endosome membrane • spindle midzone • extracellular exosome Biological process • chromosome segregation • mitotic nuclear division • small GTPase mediated signal transduction • cell division Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	127829	68724
Ensembl	ENSG00000143862	ENSMUSG00000026426
UniProt	Q96BM9	Q8VEH3
RefSeq (mRNA)	NM_001256129	NM_026823
RefSeq (protein)	NP_001243058	NP_081099
Location (UCSC)	Chr 1: 202.13 – 202.14 Mb	Chr 1: 135.15 – 135.16 Mb
PubMed search

ADP-ribosylation factor-like protein 8A is a protein that in humans is encoded by the ARL8A gene.^[1][2]

References

1. Bonaldo MF, Lennon G, Soares MB (May 1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
2. "Entrez Gene: ARL8A ADP-ribosylation factor-like 8A".

Further reading

• Gregory SG, Barlow KF, McLay KE; et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
• Hofmann I, Munro S (2006). "An N-terminally acetylated Arf-like GTPase is localised to lysosomes and affects their motility.". J. Cell. Sci. 119 (Pt 8): 1494–503. doi:10.1242/jcs.02958. PMID 16537643.
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Okai T, Araki Y, Tada M; et al. (2005). "Novel small GTPase subfamily capable of associating with tubulin is required for chromosome segregation.". J. Cell. Sci. 117 (Pt 20): 4705–15. doi:10.1242/jcs.01347. PMID 15331635.
• Secombe J, Parkhurst SM (2004). "Drosophila Topors is a RING finger-containing protein that functions as a ubiquitin-protein isopeptide ligase for the hairy basic helix-loop-helix repressor protein.". J. Biol. Chem. 279 (17): 17126–33. doi:10.1074/jbc.M310097200. PMID 14871887.
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.