ARL8B

ADP-ribosylation factor-like 8B
PDB rendering based on 1zd9.
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 2AL7​
Identifiers
Symbols	ARL8B ; ARL10C; Gie1
External IDs	MGI: 1914416 HomoloGene: 10056 GeneCards: ARL8B Gene
Gene ontology Molecular function • GTPase activity • GTP binding • GDP binding • alpha-tubulin binding • beta-tubulin binding Cellular component • cytoplasm • lysosomal membrane • membrane • midbody • late endosome membrane • spindle midzone • extracellular exosome Biological process • cell cycle • chromosome segregation • small GTPase mediated signal transduction • cell division Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	55207	67166
Ensembl	ENSG00000134108	ENSMUSG00000030105
UniProt	Q9NVJ2	Q9CQW2
RefSeq (mRNA)	NM_018184	NM_026011
RefSeq (protein)	NP_060654	NP_080287
Location (UCSC)	Chr 3: 5.12 – 5.18 Mb	Chr 6: 108.78 – 108.82 Mb
PubMed search

ADP-ribosylation factor-like protein 8B is a protein that in humans is encoded by the ARL8B gene.^[1][2]

References

1. Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
2. "Entrez Gene: ARL8B ADP-ribosylation factor-like 8B".

Further reading

• Bagshaw RD, Callahan JW, Mahuran DJ (2006). "The Arf-family protein, Arl8b, is involved in the spatial distribution of lysosomes.". Biochem. Biophys. Res. Commun. 344 (4): 1186–91. doi:10.1016/j.bbrc.2006.03.221. PMID 16650381.
• Hofmann I, Munro S (2006). "An N-terminally acetylated Arf-like GTPase is localised to lysosomes and affects their motility.". J. Cell. Sci. 119 (Pt 8): 1494–503. doi:10.1242/jcs.02958. PMID 16537643.
• Barrios-Rodiles M, Brown KR, Ozdamar B; et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells.". Science 307 (5715): 1621–5. doi:10.1126/science.1105776. PMID 15761153.
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Okai T, Araki Y, Tada M; et al. (2005). "Novel small GTPase subfamily capable of associating with tubulin is required for chromosome segregation.". J. Cell. Sci. 117 (Pt 20): 4705–15. doi:10.1242/jcs.01347. PMID 15331635.
• Secombe J, Parkhurst SM (2004). "Drosophila Topors is a RING finger-containing protein that functions as a ubiquitin-protein isopeptide ligase for the hairy basic helix-loop-helix repressor protein.". J. Biol. Chem. 279 (17): 17126–33. doi:10.1074/jbc.M310097200. PMID 14871887.
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.