AZI1

Centrosomal protein 131kDa
Identifiers
Symbols	CEP131 ; AZ1; AZI1; ZA1
External IDs	OMIM: 613479 MGI: 107440 HomoloGene: 7638 GeneCards: CEP131 Gene
Gene ontology Molecular function • molecular_function • protein binding • protein complex binding • protein homodimerization activity Cellular component • acrosomal vesicle • nucleus • nucleoplasm • centrosome • centriole • microtubule organizing center • cytosol • cilium • microtubule cytoskeleton • nuclear membrane • centriolar satellite • intracellular membrane-bounded organelle • intercellular bridge Biological process • G2/M transition of mitotic cell cycle • mitotic cell cycle • organelle organization • multicellular organismal development • spermatogenesis • positive regulation of cell proliferation • regulation of centrosome duplication • cell differentiation • intraciliary transport involved in cilium morphogenesis • positive regulation of intracellular protein transport Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	22994	12009
Ensembl	ENSG00000141577	ENSMUSG00000039781
UniProt	Q9UPN4	Q62036
RefSeq (mRNA)	NM_001009811	NM_009734
RefSeq (protein)	NP_001009811	NP_033864
Location (UCSC)	Chr 17: 81.19 – 81.22 Mb	Chr 11: 120.06 – 120.09 Mb
PubMed search

5-azacytidine-induced protein 1 is a protein that in humans is encoded by the AZI1 gene.^[1][2][3][4]

References

1. Kikuno R, Nagase T, Ishikawa K, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (1999). "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (3): 197–205. doi:10.1093/dnares/6.3.197. PMID 10470851.
2. Aoto H, Miyake Y, Nakamura M, Tajima S (1997). "Genomic organization of the mouse AZ1 gene that encodes the protein localized to preacrosomes of spermatids". Genomics 40 (1): 138–41. doi:10.1006/geno.1996.4546. PMID 9070930.
3. Andersen JS, Wilkinson CJ, Mayor T, Mortensen P, Nigg EA, Mann M (2003). "Proteomic characterization of the human centrosome by protein correlation profiling". Nature 426 (6966): 570–4. doi:10.1038/nature02166. PMID 14654843.
4. "Entrez Gene: AZI1 5-azacytidine induced 1".

Further reading

• Aoto H, Tsuchida J, Nishina Y, Nishimune Y, Asano A, Tajima S (1995). "Isolation of a novel cDNA that encodes a protein localized to the pre-acrosome region of spermatids". Eur. J. Biochem. 234 (1): 8–15. doi:10.1111/j.1432-1033.1995.008_c.x. PMID 8529672.
• Bonaldo MF, Lennon G, Soares MB (1996). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
• Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.
• Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.