Acetoxycycloheximide

Acetoxycycloheximide
Names
IUPAC name
(1R,3S,5S)-3-[(1R)-2-(2,6-Dioxo-4-piperidinyl)-1-hydroxyethyl]-1,5-dimethyl-4-oxocyclohexyl acetate
Other names
Acetyloxycycloheximide
E-73
Identifiers
2885-39-4
ChemSpider 66113
Jmol interactive 3D Image
PubChem 73396
Properties
C17H25NO6
Molar mass 339.39 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Acetoxycycloheximide is an organic chemical compound. It can be considered as the acetylated analogue of cycloheximide. It is a potent reversible inhibitor of protein synthesis in animal cells[1] and can inhibit the formation of memories.[2][3]

See also

References

  1. Mahy, Brian W J (2001). A dictionary of virology (3. ed.). San Diego, Calif. [u.a.]: Academic Press. p. 2. ISBN 0-12-465327-8.
  2. Flood, James F.; Bennett, Edward L.; Orme, Ann E.; Rosenzweig, Mark R. (February 1975). "Effects of protein synthesis inhibition on memory for active avoidance training". Physiology & Behavior 14 (2): 177–184. doi:10.1016/0031-9384(75)90163-8.
  3. Flexner, L. B.; Flexner, J. B.; Roberts, R. B. (1 August 1966). "Stages of memory in mice treated with acetoxycycloheximide before or immediately after learning.". Proceedings of the National Academy of Sciences 56 (2): 730–735. doi:10.1073/pnas.56.2.730.
This article is issued from Wikipedia - version of the Tuesday, August 25, 2015. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.