Alan Brash (pharmacologist)

Alan Richard Brash (born 1949) is a professor of pharmacology at Vanderbilt University.[1] He is a leading authority on the biosynthesis of prostoglandins and eicosanoids.[1]

Biography

Education

Brash was educated at Strathallan School near Perth, Scotland and Downing College, Cambridge, where he was elected a scholar.[2] He graduated with a BA in medical sciences in 1970 and proceeded to the University of Edinburgh to study for his PhD, graduating in 1976.[3] Brash was then appointed a research fellow in the Department of Clinical Pharmacology at the Royal Postgraduate Medical School in London.[3] Thereafter, he moved to Vanderbilt University.[3]

Research

During his time at Vanderbilt, Brash's research has focused on the analysis of the mechanisms of formation and transformation of lipoxygenase products with an interest in their physiological role.[3] His findings have initiated further research on stereochemical aspects of lipoxygenase catalysis and on the role of epithelial lipoxygenases.[3]

Furthermore, his research has led to more work on the biochemistry of the CYP74 family of cytochrome P450s, and on the catalase-related hemoproteins which also metabolize fatty acid hydroperoxides.[3] As of 2009 he had published almost 200 research papers.[4]

In October 2013 he was elected a Fellow of the American Association for the Advancement of Science.[5]

References

  1. 1 2 "Vanderbilt celebrates 18 elected fellows of the AAAS". Vanderbilt University. 25 November 2013. Retrieved 29 October 2015.
  2. "A R Brash" (PDF). The Strathallian. Vol. 9 no. 3. Autumn 1970. p. 13. Retrieved 29 October 2015.
  3. 1 2 3 4 5 6 Brash, Alan R (September 2009). "Mechanistic aspects of CYP74 allene oxide synthases and related cytochrome P450 enzymes". Phytochemistry 70 (13-14): 1522–1531. doi:10.1016/j.phytochem.2009.08.005. PMC 2783490. PMID 19747698.
  4. List of publications from Microsoft Academic Search
  5. "AAAS Members Elected as Fellows" (PDF). Science. 29 November 2013. p. 1064. Retrieved 29 October 2015.

External links

Official website


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