Alan J. Cooper

Alan J. Cooper (born 1966)[1] is a New Zealand evolutionary molecular biologist and Ancient DNA researcher. He is the director of the Australian Centre for Ancient DNA at the University of Adelaide, South Australia.[2]

Early life and education

Cooper was born in Dunedin, New Zealand and grew up in Wellington, New Zealand where he was involved in cave exploration at university and regional level. He performed his PhD research at the University of California, Berkeley under Allan C. Wilson and Svante Pääbo, graduating from Victoria University of Wellington with a PhD in Biochemistry and Genetics in 1994.[1]

Academic career

Cooper is known as one of the pioneers of ancient DNA research, performing some of the first PCR-based studies with Svante Paabo and Allan C. Wilson at UC Berkeley in 1989. In 2001, he used these methods to characterise the first complete genome sequences from an extinct species, mitochondrial genomes from two New Zealand moa.[3]

Cooper established the Henry Wellcome Ancient Biomolecules Centre at the University of Oxford in 1999, which he directed until 2005.[4] He became Professor of Ancient Biomolecules at Oxford in 2002.[5] In 2004, he was awarded an Australian Research Council Federation Fellowship to establish the Australian Centre for Ancient DNA at the University of Adelaide, South Australia where he is the Director.[6]

Cooper has analysed ancient DNA from extinct species preserved in permafrost areas of Alaska and the Yukon,[7] and cave and archaeological deposits around the world. He has published on the evolutionary history of enigmatic extinct species such as: New Zealand moa and Madagascan elephant bird (Aepyornis), the dodo, American lion (P. leo atrox) and cheetah-like cat (Miracinonyx), North and South American horses (stilt-legged horse, Hippidion), steppe bison, bears (Arctodus, U. arctos), cave hyenas (Crocuta spelaea) and the Falkland Islands wolf (Dusicyon australis). He has also shown that the calcified plaque on the teeth of ancient skeletons can be used to reconstruct the evolution of the human microbiome through time.[8]

In 2000, with Dr Henrik Poinar, he suggested that the standards of much ancient DNA research were insufficient to rule out contamination, especially in studies of ancient humans.[9] He has also published a series of papers showing that the molecular clock changes speed according to the time period used to measure it.[10][11]

Notable Awards

External links

References

  1. 1 2 "Alpha Series Issue 115: Alan Cooper", Royal Society of New Zealand, March 2003. Retrieved on 18 October 2014.
  2. ↑ "RiAus: Alan Cooper", Royal Institution of Australia, Retrieved on 18 October 2014.
  3. ↑ Cooper A, Lalueza-Fox C, Anderson S, Rambaut A, Austin J, Ward R. "Complete mitochondrial genome sequences of two extinct moas clarify ratite evolution." Nature 409:704-707 (2001).
  4. ↑ "Oxford DNA lab leaderless" The Scientist 2 June 2005. Retrieved on 7 December 2014
  5. ↑ "Supplement 1: Recognition of Distinction" Oxford University Gazette 26 September 2002. Retrieved on 18 October 2014
  6. ↑ "TedX: Alan Cooper" "TedX Adelaide" 8 April 2013. Retrieved on 18 October 2014
  7. ↑ Kahn, Jennifer. "Canada's Ancient Monsters on Ice", Discover, 28 March 2004. Retrieved on 18 October 2014
  8. ↑ Adler CJ, Dobney K, Weyrich L, Kaidonis J, Walker AW, Haak W, Bradshaw CJA, Townsend G, Soltysiak A, Alt KW, Parkhill J, Cooper A. "Sequencing ancient calcified dental plaque shows changes in oral microbiota with dietary shifts of the Neolithic and Industrial Revolutions." Nature Genetics 45:450-455 (2013).
  9. ↑ Cooper A, Poinar HN. "Ancient DNA: Do it right or not at all." Scince 289:1139 (2000).
  10. ↑ Ho SYW, Phillips MJ, Cooper A, Drummond AJ. "Time dependency of molecular rate estimates and systematic overestimation of recent divergence times." Mol Biol Evol 22:1561-1568 (2005).
  11. ↑ Ho SYW, Lanfear R, Bromham L, Phillips MJ, Soubrier J, Rodrigo AG, Cooper A. "Time dependent rates of molecular evolution." Molecular Ecology 20:3087-3101 (2011).
  12. ↑ "Australian Research Council Laureate Fellowship: Alan Cooper" "Australian Research Council" Retrieved on 7 December 2014
  13. ↑ "Australian Centre for Ancient DNA: Research" Retrieved on 7 December 2014
  14. ↑ "Australian Research Council Future Fellowships 2009" "Australian Research Council" Retrieved on 7 December 2014
  15. ↑ "Australian Research Council Federation Fellowships 2004" "Australian Research Council" Retrieved on 7 December 2014
  16. ↑ "Annual Report of the Institute of Zoology 2001/02" [Zoological Society of London] Retrieved on 7 December 2014
  17. ↑ "Philip Leverhulme Prizes 2002" "The Leverhulme Trust" Retrieved on 7 December 2014
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