Alkaline hydrolysis

Script error: The module returned a value. It is supposed to return an export table. Alkaline hydrolysis, in organic chemistry, usually refers to types of nucleophilic substitution reactions in which the attacking nucleophile is a hydroxide ion.

Example

In the alkaline hydrolysis of esters and amides the hydroxide ion nucleophile attacks the carbonyl carbon in a nucleophilic acyl substitution reaction. This mechanism is supported by isotope labeling experiments. For example, when ethyl propionate with an oxygen-18 labeled ethoxy group is treated with sodium hydroxide (NaOH), the oxygen-18 is completely absent from the sodium propionate product and is found exclusively in the ethanol formed.[1]

Uses

Drain cleaners take advantage of this method to dissolve hair and fat in pipes.

See also

References

  1. ↑ Script error: The module returned a value. It is supposed to return an export table.

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