Alkenylglycerophosphocholine hydrolase
| alkenylglycerophosphocholine hydrolase | |||||||||
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| Identifiers | |||||||||
| EC number | 3.3.2.2 | ||||||||
| CAS number | 37288-65-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / EGO | ||||||||
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In enzymology, an alkenylglycerophosphocholine hydrolase (EC 3.3.2.2) is an enzyme that catalyzes the chemical reaction
- 1-(1-alkenyl)-sn-glycero-3-phosphocholine + H2O
an aldehyde + sn-glycero-3-phosphocholine
Thus, the two substrates of this enzyme are 1-(1-alkenyl)-sn-glycero-3-phosphocholine and H2O, whereas its two products are aldehyde and sn-glycero-3-phosphocholine.
This enzyme belongs to the family of hydrolases, specifically those acting on ether bonds (ether hydrolases). The systematic name of this enzyme class is 1-(1-alkenyl)-sn-glycero-3-phosphocholine aldehydohydrolase. This enzyme is also called lysoplasmalogenase. This enzyme participates in ether lipid metabolism.
References
- Arthur G, Page L, Mock T, Choy PC (1986). "The catabolism of plasmenylcholine in the guinea pig heart". Biochem. J. 236 (2): 475–80. PMC 1146864. PMID 3753461.
- Ellingson JS and Lands WEM (1968). "Phospholipid reactivation of plasmalogen metabolism". Lipids 3 (2): 111–120. doi:10.1007/BF02531727. PMID 17805898.
- Warner HR and Lands WEM (1961). "The metabolism of plasmalogen: enzymatic hydrolysis of the vinyl ether" (PDF). J. Biol. Chem. 236 (9): 2404–2409. PMID 13783189.
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