Alkylphosphocholine

Alkylphosphocholines are phospholipid-like molecules that have been synthesised, which have remarkable biological and therapeutic activities.[1][2] They are phosphocholine esters of aliphatic long chain alcohols differing in chain length, Unsaturation and position of the cis-double bond.[3]

References

  1. ↑ Unger C, Sindermann H, Peukert M, Hilgard P, Engel J, Eibl H (1992). "Hexadecylphosphocholine in the topical treatment of skin metastases in breast cancer patients". Progress in Experimental Tumor Research. Fortschritte Der Experimentellen Tumorforschung. Progrès De La Recherche Expérimentale Des Tumeurs 34: 153–9. PMID 1438798.
  2. ↑ Zeisig R, Jungmann S, Fichtner I, Daemen T, Arndt D (1994). "Cytotoxic effects of alkylphosphocholines or alkylphosphocholine-liposomes and macrophages on tumor cells". Anticancer Research 14 (5A): 1785–9. PMID 7847811.
  3. ↑ Dieter Arndt, Reiner Zeisig, Ines Eue and Iduna Fichtner (1995). "Alkylphosphocholines and Alkylphosphocholine Liposomes" 5 (1): 91–98. doi:10.3109/08982109509039910.


This article is issued from Wikipedia - version of the Thursday, September 12, 2013. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.