Amylmetacresol
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| Systematic (IUPAC) name | |
|---|---|
|
5-methyl-2-pentylphenol | |
| Clinical data | |
| AHFS/Drugs.com | International Drug Names |
| Routes of administration | Oral |
| Legal status | |
| Identifiers | |
| CAS Number | 53043-14-4 |
| ATC code | R02AA20 (WHO) |
| PubChem | CID 14759 |
| ChemSpider |
14076  |
| ChEMBL | CHEMBL1512677 |
| Chemical data | |
| Formula | C12H18O |
| Molar mass | 178.27 |
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| |
| (verify) | |
Amylmetacresol (AMC) is an antiseptic used to treat infections of the mouth and throat. It is used as an active pharmaceutical ingredient in Strepsils, Cēpacol, Gorpils and Lorsept throat lozenges.
Chemically, AMC is derivative of m-cresol, with a pentyl group attached to the sixth carbon atom. The pure substance melts at 24°C, and boils between 137 to 139°C (at 6.7 kPa). It is soluble in water, ethanol, acetone, ether, and oil. AMC exhibits low toxicity, and a RW coefficient of 250.[1]
See also
References
- ↑ Twort, CC; Baker, AH (1942). "Further Researches on Bactericidal Mists and Smokes". The Journal of Hygiene 42 (3): 266–283. doi:10.1017/s0022172400035476. PMC 2199819. PMID 20475630.
External links
- C. E. Coulthard (1931). "The Disinfectant and Antiseptic Properties of Amyl-meta-cresol". J Exp Patho 12 (5): 331–336. Retrieved 29 November 2015.
- Oxford JS, Lambkin R, Gibb I, Balasingam S, Chan C, Catchpole A. (2005). "A throat lozenge containing amyl meta cresol and dichlorobenzyl alcohol has a direct virucidal effect on respiratory syncytial virus, influenza A and SARS-CoV". Antivir Chem Chemother 16 (2): 129–34. Retrieved 29 November 2015.
- McNally D, Shephard A, Field E. (2012). "Randomised, double-blind, placebo-controlled study of a single dose of an amylmetacresol/2,4-dichlorobenzyl alcohol plus lidocaine lozenge or a hexylresorcinol lozenge for the treatment of acute sore throat due to upper respiratory tract infection". J Pharm Pharm Sci 15 (2): 281–94. Retrieved 29 November 2015.
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