Andrastin A

Andrastin A

Identifiers
Jmol interactive 3D	Image
PubChem	6712564
SMILES CC1C(=O)[C@@]2(C(=C[C@@H]3[C@@]([C@@]2(C1=O)C(=O)OC)(CC[C@H]4[C@]3(CC[C@@H](C4(C)C)OC(=O)C)C=O)C)C)C
Properties
Chemical formula	C28H38O7
Molar mass	486.61 g·mol^−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Andrastin A is a farnesyltransferase inhibitor isolate of Penicillium species including Penicillium albocoremium^[1] and Penicillium roqueforti.^[2]

References

1. Overy DP, Larsen TO, Dalsgaard PW, Frydenvang K, Phipps R, Munro MH, Christophersen C. (2005). "Andrastin A and barceloneic acid metabolites, protein farnesyl transferase inhibitors from Penicillium albocoremium: chemotaxonomic significance and pathological implications". Mycol Res 109 (Pt 11): 1243–1249. doi:10.1017/S0953756205003734. PMID 16279417.
2. Nielsen KF, Dalsgaard PW, Smedsgaard J, Larsen TO (April 2005). "Andrastins A-D, Penicillium roqueforti Metabolites consistently produced in blue-mold-ripened cheese". J. Agric. Food Chem. 53 (8): 2908–13. doi:10.1021/jf047983u. PMID 15826038.