Antibiotic synergy

Antibiotic synergy occurs when multiple antibiotics are used to treat an infection and their response is stronger or faster than what use of a single antibiotic is.[1] It is opposed to antibiotic antagonism. [1]

One example of antibiotic synergy occurs upon combined use of aminoglycosides and beta-lactam antibiotics, where synergy is explained by increased uptake of aminoglycosides following increased permeability caused from beta-lactam antibiotics.[1]

References

  1. 1 2 3 Kohanski, MA; Dwyer, DJ; Collins, JJ (June 2010). "How antibiotics kill bacteria: from targets to networks.". Nature reviews. Microbiology 8 (6): 423–35. doi:10.1038/nrmicro2333. PMID 20440275.
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