Aspartate N-acetyltransferase

aspartate N-acetyltransferase
Identifiers
EC number	2.3.1.17
CAS number	9029-99-6
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, an aspartate N-acetyltransferase (EC 2.3.1.17) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + L-aspartate $\rightleftharpoons$ CoA + N-acetyl-L-aspartate

Thus, the two substrates of this enzyme are acetyl-CoA and L-aspartate, whereas its two products are CoA and N-acetyl-L-aspartate.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:L-aspartate N-acetyltransferase. Other names in common use include aspartate acetyltransferase, and L-aspartate N-acetyltransferase.

References

• Goldstein FB (1959). "Biosynthesis of N-acetyl-L-aspartic acid". J. Biol. Chem. 234: 2702–2706.
• Knizley H Jr (1967). "The enzymatic synthesis of N-acetyl-L-aspartic acid by a water-insoluble preparation of a cat brain acetone powder". J. Biol. Chem. 242 (20): 4619–22. PMID 6061408.