Azadipyrromethene

An azadipyrromethene, here ADPM06.

Azadipyrromethene (ADPM) is a dye and the name of a new class of experimental photosensitizers for photodynamic therapy.[1][2]

Some derivatives can usefully absorb in the near-infrared.[3]

See Also

References

  1. ↑ Gallagher, W M; Allen, L T; O'Shea, C; Kenna, T; Hall, M; Gorman, A; Killoran, J; O'Shea, D F (19 April 2005). "A potent nonporphyrin class of photodynamic therapeutic agent: cellular localisation, cytotoxic potential and influence of hypoxia". British Journal of Cancer 92 (9): 1702–1710. doi:10.1038/sj.bjc.6602527.
  2. ↑ Byrne, A T; O'Connor, A E; Hall, M; Murtagh, J; O'Neill, K; Curran, K M; Mongrain, K; Rousseau, J A; Lecomte, R; McGee, S; Callanan, J J; O'Shea, D F; Gallagher, W M (13 October 2009). "Vascular-targeted photodynamic therapy with BF2-chelated Tetraaryl-Azadipyrromethene agents: a multi-modality molecular imaging approach to therapeutic assessment". British Journal of Cancer 101 (9): 1565–1573. doi:10.1038/sj.bjc.6605247.
  3. ↑ McDonnell, Shane O.; O'Shea, Donal F. (August 2006). "Near-Infrared Sensing Properties of Dimethlyamino-Substituted BF −Azadipyrromethenes". Organic Letters 8 (16): 3493–3496. doi:10.1021/ol061171x.


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