Copanlisib

Copanlisib
Names
IUPAC name
2-Amino-N-[7-methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl]pyrimidine-5-carboxamide
Other names
BAY 80-6946
Identifiers
1032568-63-0
ChEMBL ChEMBL3218576
ChemSpider 25069683
Jmol interactive 3D Image
MeSH 2-amino-N-(7-methoxy-8-(3-morpholinopropoxy)-2,3-dihydroimidazo(1,2-c)quinazolin-4-yl)pyrimidine-5-carboxamide
UNII WI6V529FZ9
Properties
C23H28N8O4
Molar mass 480.53 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Copanlisib (BAY 80-6946), developed by Bayer, is a selective Class I phosphoinositide 3-kinase inhibitor[1] which has shown promise in Phase I/II clinical trials for the treatment of non-Hodgkin lymphoma and chronic lymphocytic leukemia.[2]

References

  1. "Phase II Data of Bayer’s Novel Cancer Drug Candidate Copanlisib to be Presented". Retrieved 3 March 2015.
  2. Loguidice, Christina (8 December 2014). "Copanlisib Continues to Show Promise for Treating Indolent Lymphomas". Rare Disease Report. Retrieved 3 March 2015.
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