BICD2

Bicaudal D homolog 2 (Drosophila)
Identifiers
Symbols BICD2 ; SMALED2; bA526D8.1
External IDs OMIM: 609797 MGI: 1924145 HomoloGene: 9070 GeneCards: BICD2 Gene
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 23299 76895
Ensembl ENSG00000185963 ENSMUSG00000037933
UniProt Q8TD16 Q921C5
RefSeq (mRNA) NM_001003800 NM_001039179
RefSeq (protein) NP_001003800 NP_001034268
Location (UCSC) Chr 9:
92.71 – 92.76 Mb
Chr 13:
49.34 – 49.39 Mb
PubMed search

Protein bicaudal D homolog 2 is a protein that in humans is encoded by the BICD2 gene.[1][2]

This gene is one of two human homologs of Drosophila bicaudal-D and a member of the Bicoid family. It has been implicated in dynein-mediated, minus end-directed motility along microtubules. It has also been reported to be a phosphorylation target of NIMA related kinase 8. Two alternative splice variants have been described.[2]

References

  1. Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Dec 1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res 5 (3): 169–76. doi:10.1093/dnares/5.3.169. PMID 9734811.
  2. 1 2 "Entrez Gene: BICD2 bicaudal D homolog 2 (Drosophila)".

Further reading


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