Bang senseless

Bang senseless (bss) is a gene identified in Drosophila melanogaster that is known to yield seizure-like activity in mutant phenotypes.[1]

Location

Bang senseless has been localized to 1-54, left of forked (f) and right of scalloped (sd).[1]

Inducing seizure activity

Seizures can be induced by mechanical shock, electrical shock, or high-frequency visual stimuli such as strobe lights. Mechanical shock can be achieved by vortexing bang senseless mutants in a small vial for ~10 seconds on a VWR vortex set to its maximum setting.[2]

Alleles

Aside from the wild-type allele, two mutant alleles have been identified: bss1 & bss2.

bss1

The bss1 mutants typically recover from seizure after 100–400 seconds.[2]

bss2

Less is known about the bss2 allele, but it is known that it is also a paralytic mutant (prone to seizure-like activity).[3]

References

  1. 1 2 Bang senseless report @ FlyBase.org
  2. 1 2 bss1 report @ FlyBase.org
  3. ↑ bss2 report @ FlyBase.org


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