Benzamidine
 | |
 | |
| Names | |
|---|---|
| IUPAC name
Benzenecarboximidamide | |
| Identifiers | |
618-39-3  | |
| ChEBI | CHEBI:41033 |
| ChEMBL | ChEMBL20936 |
| ChemSpider | 2242 |
| 7566 | |
| Jmol 3D model | Interactive image |
| KEGG | C01784 |
| PubChem | 2332 |
| |
| |
| Properties | |
| C7H8N2 | |
| Molar mass | 120.15 g/mol |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
verify (what is  ?) | |
| Infobox references | |
Benzamidine is a reversible competitive inhibitor of trypsin, trypsin-like enzymes and serine proteases.
It is often used as a ligand in protein crystallography to prevent proteases from degrading a protein of interest; the triangular diamine group at the bottom gives it a very obvious 'stick-man' shape which shows up in difference density maps. The benzamidine moiety is also found in some pharmaceuticals, like dabigatran.
This article is issued from Wikipedia - version of the Monday, April 04, 2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.