Beta-apo-4'-carotenal oxygenase

Beta-apo-4'-carotenal oxygenase
Identifiers
EC number	1.2.1.82
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Beta-apo-4'-carotenal oxygenase (EC 1.2.1.82, beta-apo-4'-carotenal dehydrogenase, YLO-1, carD (gene)) is an enzyme with systematic name 4'-apo-beta,psi-carotenal:NAD⁺ oxidoreductase.^[1][2] This enzyme catalyses the following chemical reaction:

4'-apo-beta,psi-caroten-4'-al + NAD⁺ + H2O $\rightleftharpoons$ neurosporaxanthin + NADH + 2 H⁺

Neurosporaxanthin is responsible for the orange color of Neurospora.

References

1. Estrada, A.F., Youssar, L., Scherzinger, D., Al-Babili, S. and Avalos, J. (2008). "The ylo-1 gene encodes an aldehyde dehydrogenase responsible for the last reaction in the Neurospora carotenoid pathway". Mol. Microbiol. 69 (5): 1207–1220. doi:10.1111/j.1365-2958.2008.06349.x. PMID 18627463.
2. Diaz-Sanchez, V., Estrada, A.F., Trautmann, D., Al-Babili, S. and Avalos, J. (2011). "The gene carD encodes the aldehyde dehydrogenase responsible for neurosporaxanthin biosynthesis in Fusarium fujikuroi". FEBS J. 278 (17): 3164–3176. doi:10.1111/j.1742-4658.2011.08242.x. PMID 21749649.

External links

• Beta-apo-4'-carotenal oxygenase at the US National Library of Medicine Medical Subject Headings (MeSH)