List of largest biotechnology companies

A biotechnology company is a company whose products or services primarily use biotechnology methods for their production, design or delivery. The United Nations Convention on Biological Diversity defines 'biotechnology' as: "Any technological application that uses biological systems, living organisms, or derivatives thereof, to make or modify products or processes for specific use."^[1] In other words, biotechology can be defined as the mere application of technical advances in life science to develop commercial products. Today, no comprehensive global database of biotech companies is available online, despite the fact that a free and open access project was launched in late 2014.^[2]

Independent biotechnology companies

• The following is a list of the top 25 independent biotechnology companies listed on a stock exchange ranked by Market Capitalization as of June 2015 (Q3 2015).
• Note that it does not include biotechnology companies that are now owned by, or part of, larger pharmaceutical groups.

Rank	Change	Company	Country	Highest Market Cap ever (historical)(USD billions)	Market Cap in Q1 2016 (USD billions)[3][4]	Market Cap in 2015 (USD billions)[5]	Market Cap in 2014 (USD billions)[6]	Market Cap in 2013 (USD billions)
1		Johnson & Johnson	United States	306.4 September 2014	298.9	284.2	277.8	258.3
2		Roche	Switzerland	263.6 February 2014	208.8	234.7	258.5	240.3
3		Novartis	Switzerland	275.2 July 2015	195.2	206.1	229.8	195.0
4		Pfizer	United States	310.5 July 2000	186.4	199.3	205.4	196.0
5		Merck & Co.	United States	178.9 January 2015	148.0	147.6	166.9	146.5
6		Gilead Sciences	United States	179.6 June 2013	124.9	145.8	109.0	78.4
7		Amgen	United States	130.6 December 2014	113.3	122.5	93.1	78.7
8		Novo Nordisk	Denmark	153.8 June 2015	112.0	153.9	125.4	19.6
9		Sanofi	France	151.3 September 2014	106.6	111.8	138.1	142.0
10		Bristol-Myers Squibb	United States	115.3 May 2015	105.4	114.8	97.6	87.2
11		GlaxoSmithKline	United Kingdom	174.9 May 2006	100.2	97.6	128.9	129.6
12		Bayer	Germany	129 March 2015	97.1	103.2	113.2	117.4
13		AbbVie	United States	112.2 June 2015	92.5	96.8	104.1	83.8
14		Eli Lilly & Co	United States	122.6 August 2000	79.7	93.4	76.6	57.0
15		Celgene	United States	102.9 March 2015	77.6	94.1	89.5	69.2
16		AstraZeneca	United Kingdom	102.9 October 2006	70.9	85.8	88.9	74.6
17		Abbott Laboratories	United States	74.8 July 2015	62.0	67.0	67.9	59.3
18		Biogen Idec	United States	111.7 March 2015	56.6	68.3	79.7	66.1
19		Teva Pharmaceutical	Israel	58.9 April 2010	54.1	55.9	49.0	37.8
20		Stryker Corporation	United States	40.2 March 2016	40.2	34.7	35.7	28.4
21		Regeneron Pharmaceuticals Inc	United States	56.5 December 2015	37.3	56.5	42.0	27.4
22		Shire Pharmaceuticals	Ireland	52.4 October 2014	34.0	41.0	42.4	28.1
23		Alexion Pharmaceuticals	United States	43.1 June 2015	31.6	43.0	36.8	26.2
24		Baxalta Inc	United States	27.5 April 2015	27.5	27.5	21.2	16.1
25		Mylan	United States	37.2 April 2015	22.8	26.6	21.2	16.1

Milestones

• Q1 2016
  • Valeant exits the top-25 list with a decrease in market cap of $25 billion.
  • Allergan, plc exits the list due to its merger with Pfizer.
  • Stryker & Baxalta enter the top-25

References

1. "The Convention on Biological Diversity (Article 2. Use of Terms)." United Nations. 1992. Retrieved on February 6, 2008.
2. Carlo Alberto Oppici, Filippo Giancarlo Martinelli. "BioDirecta". Retrieved 22 March 2015.
3. "Healthcare – Google Finance".
4. "Healthcare – Google Finance".
5. "The World’s Biggest Public Companies". Forbes.
6. "• Top biotech and pharmaceutical companies market value 2015 - Statistic". Statista.

External links

• BioPharmGuy: Biotech database established in 2008. Sortable by location or business type
• Another List of Biotechnology Companies
• BioDirecta: the most comprehensive free database of biotech and pharma companies