Biotin-independent malonate decarboxylase
Biotin-independent malonate decarboxylase (EC 4.1.1.88, malonate decarboxylase (without biotin), malonate decarboxylase, MDC) is an enzyme with systematic name malonate carboxy-lyase (biotin-independent).[1][2][3][4][5][6][7][8][9] This enzyme catalyses the following chemical reaction
- malonate + H+ acetate + CO2
Two types of malonate decarboxylase are currently known, both of which form multienzyme complexes.
References
- ↑ Schmid, M., Berg, M., Hilbi, H. and Dimroth, P. (1996). "Malonate decarboxylase of Klebsiella pneumoniae catalyses the turnover of acetyl and malonyl thioester residues on a coenzyme-A-like prosthetic group". Eur. J. Biochem. 237: 221–228. doi:10.1111/j.1432-1033.1996.0221n.x. PMID 8620876.
- ↑ Byun, H.S. and Kim, Y.S. (1997). "Subunit organization of bacterial malonate decarboxylases: the smallest δ subunit as an acyl-carrier protein". J. Biochem. Mol. Biol. 30: 132–137.
- ↑ Hoenke, S., Schmid, M. and Dimroth, P. (1997). "Sequence of a gene cluster from Klebsiella pneumoniae encoding malonate decarboxylase and expression of the enzyme in Escherichia coli". Eur. J. Biochem. 246: 530–538. doi:10.1111/j.1432-1033.1997.00530.x. PMID 9208947.
- ↑ Chohnan, S., Fujio, T., Takaki, T., Yonekura, M., Nishihara, H. and Takamura, Y. (1998). "Malonate decarboxylase of Pseudomonas putida is composed of five subunits". FEMS Microbiol. Lett. 169: 37–43. doi:10.1111/j.1574-6968.1998.tb13296.x. PMID 9851033.
- ↑ Hoenke, S., Schmid, M. and Dimroth, P. (2000). "Identification of the active site of phosphoribosyl-dephospho-coenzyme A transferase and relationship of the enzyme to an ancient class of nucleotidyltransferases". Biochemistry 39: 13233–13240. doi:10.1021/bi001154u. PMID 11052676.
- ↑ Handa, S., Koo, J.H., Kim, Y.S. and Floss, H.G. (1999). "Stereochemical course of biotin-independent malonate decarboxylase catalysis". Arch. Biochem. Biophys. 370: 93–96. doi:10.1006/abbi.1999.1369. PMID 10496981.
- ↑ Koo, J.H. and Kim, Y.S. (1999). "Functional evaluation of the genes involved in malonate decarboxylation by Acinetobacter calcoaceticus". Eur. J. Biochem. 266: 683–690. doi:10.1046/j.1432-1327.1999.00924.x. PMID 10561613.
- ↑ Kim, Y.S. (2002). "Malonate metabolism: biochemistry, molecular biology, physiology, and industrial application". J. Biochem. Mol. Biol. 35: 443–451. doi:10.5483/bmbrep.2002.35.5.443. PMID 12359084.
- ↑ Dimroth, P. and Hilbi, H. (1997). "Enzymic and genetic basis for bacterial growth on malonate". Mol. Microbiol. 25: 3–10. doi:10.1046/j.1365-2958.1997.4611824.x. PMID 11902724.
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