Biphenyl synthase

Biphenyl synthase
Identifiers
EC number 2.3.1.177
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

In enzymology, a biphenyl synthase (EC 2.3.1.177) is an enzyme that catalyzes the chemical reaction:

3 malonyl-CoA + benzoyl-CoA \rightleftharpoons 4 CoA + 3,5-dihydroxybiphenyl + 4 CO2

Thus, the two substrates of this enzyme are malonyl-CoA and benzoyl-CoA, whereas its 3 products are CoA, 3,5-dihydroxybiphenyl, and CO2.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is malonyl-CoA:benzoyl-CoA malonyltransferase. This enzyme is also called BIS.

References

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