Bisindolylmaleimide

Bisindolylmaleimide

Names
IUPAC name 3,4-Di(1H-indol-2-yl)-1H-pyrrole-2,5-dione
Identifiers
ChemSpider	8862983
Jmol interactive 3D	Image
PubChem	10687637
InChI InChI=1S/C20H13N3O2/c24-19-17(15-9-11-5-1-3-7-13(11)21-15)18(20(25)23-19)16-10-12-6-2-4-8-14(12)22-16/h1-10,21-22H,(H,23,24,25) Key: LRBHDUWDZCAYDA-UHFFFAOYSA-N InChI=1/C20H13N3O2/c24-19-17(15-9-11-5-1-3-7-13(11)21-15)18(20(25)23-19)16-10-12-6-2-4-8-14(12)22-16/h1-10,21-22H,(H,23,24,25) Key: LRBHDUWDZCAYDA-UHFFFAOYAH
SMILES O=C5C(\c2cc1ccccc1n2)=C(\c4cc3ccccc3n4)C(=O)N5
Properties
Chemical formula	C20H13N3O2
Molar mass	327.34 g·mol^−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Bisindolylmaleimide is an organic compound that forms the core chemical structure of a variety of biologically active compounds.^[1]

Examples of bisindolylmaleimide derivatives include:

• Bisindolylmaleimide I
• Enzastaurin
• Ruboxistaurin
• Tivantinib

References

1. Faul, Margaret M.; Winneroski, Leonard L.; Krumrich, Christine A. (1998). "A New, Efficient Method for the Synthesis of Bisindolylmaleimides". The Journal of Organic Chemistry 63 (17): 6053. doi:10.1021/jo980513c. PMID 11672217.

External links

Media related to Bisindolylmaleimides at Wikimedia Commons