Blueberry muffin baby

"Blueberry muffin" appearance of blue-grey nodules under the skin, here due to neuroblastoma

Blueberry muffin baby is the characteristic distributed purpura occurring as a result of extramedullary hematopoiesis found in infants.[1][2]:826 The purpura are often generalized, but occur more often on the trunk, head, and neck.[3] The name is from the superficial similarity to a blueberry muffin.

Causes

The condition was originally considered characteristic of rubella, but is now considered to be potentially associated with many other conditions,[4] such as cytomegalovirus[5] and metastatic neuroblastoma.

See also

References

  1. Shaffer MP, Walling HW, Stone MS (August 2005). "Langerhans cell histiocytosis presenting as blueberry muffin baby". J. Am. Acad. Dermatol. 53 (2 Suppl 1): S143–6. doi:10.1016/j.jaad.2005.01.015. PMID 16021165.
  2. James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
  3. Blueberry muffin baby: A pictoral differential diagnosis Vandana Mehta, C Balachandran, Vrushali Lonikar. Dermatology Online Journal 14 (2): 8 .
  4. Mehta V, Balachandran C, Lonikar V (2008). "Blueberry muffin baby: a pictoral differential diagnosis". Dermatol. Online J. 14 (2): 8. PMID 18700111.
  5. Gaffin JM, Gallagher PG (November 2007). "Picture of the month. Blueberry muffin baby (extramedullary hematopoiesis) due to congenital cytomegalovirus infection". Arch Pediatr Adolesc Med 161 (11): 1102–3. doi:10.1001/archpedi.161.11.1102. PMID 17984414.

External links


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