Boldine
For other uses, see Boldin.
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| Identifiers | |
|---|---|
476-70-0  | |
| ChEMBL | ChEMBL388342  |
| ChemSpider | 9748 |
| Jmol interactive 3D | Image |
| PubChem | 10154 |
| UNII | 8I91GE2769 |
| |
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| Properties | |
| C19H21NO4 | |
| Molar mass | 327.38 g·mol−1 |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| verify (what is ?) | |
| Infobox references | |
Boldine is an alkaloid of the aporphine class that can be found in the boldo tree[1] and in Lindera aggregata.[2]
Boldine has antioxidant activity that effectively protects against free radical induced lipid peroxidation or enzyme inactivation. In addition, it has alpha-adrenergic antagonist activities in vascular tissue, and it has also been reported to have hepatoprotective, cytoprotective, antipyretic and anti-inflammatory effects.[3]
References
- ↑ O'Brien, P.; Carrasco-Pozo, C.; Speisky, H. (2006). "Boldine and its Antioxidant or Health-Promoting Properties". Chemico-Biological Interactions 159 (1): 1–17. doi:10.1016/j.cbi.2005.09.002. PMID 16221469.
- ↑ Han, Z.; Zheng, Y.; Chen, N.; Luan, L.; Zhou, C.; Gan, L.; Wu, Y. (2008). "Simultaneous Determination of Four Alkaloids in Lindera aggregata by Ultra-High-Pressure Liquid Chromatography–Tandem Mass Spectrometry". Journal of Chromatography A 1212 (1–2): 76–81. doi:10.1016/j.chroma.2008.10.017. PMID 18951552.
- ↑ Zhang, A.; Zhang, Y.; Branfman, A. R.; Baldessarini, R. J.; Neumeyer, J. L. (2007). "Advances in Development of Dopaminergic Aporphinoids". Journal of Medicinal Chemistry 50 (2): 171–181. doi:10.1021/jm060959i. PMID 17228858.
External links
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