Brachystemma

Brachystemma calycinum
Scientific classification
Kingdom: Plantae
(unranked): Angiosperms
(unranked): Eudicots
(unranked): Core eudicots
Order: Caryophyllales
Family: Caryophyllaceae
Genus: Brachystemma
D.Don
Species: B. calycinum
Binomial name
Brachystemma calycinum
D.Don

Brachystemma calycinum is an indigenous plant of southwestern China and has shown promise as a natural adjunct anti-inflammatory agent for treatment of osteoarthritis in humans and dogs.[1] This plant reported has active ingredients which result in decreased levels of protease activated receptor 2 (PAR 2), inducible nitric oxide synthase, and matrix metalloprotease 13.[2]

References

  1. Maxim Moreau, Bertrand Lussier, Jean-Pierre Pelletier, Johanne Martel-Pelletier, Christian Bédard, Dominique Gauvin & Eric Troncy (2012). "Brachystemma calycinum D. Don effectively reduces the locomotor disability in dogs with naturally occurring osteoarthritis: a randomized placebo-controlled trial". Evidence-based Complementary and Alternative Medicine 2012: 646191. doi:10.1155/2012/646191. PMC 3403515. PMID 22844335.
  2. Christelle Boileau, Johanne Martel-Pelletier, Judith Caron, Frédéric Paré, Eric Troncy, Maxim Moreau & Jean-Pierre Pelletier (2010). "Oral treatment with a Brachystemma calycinum D. Don plant extract reduces disease symptoms and the development of cartilage lesions in experimental dog osteoarthritis: inhibition of protease-activated receptor 2". Annals of the Rheumatic Diseases 69 (6): 1179–1184. doi:10.1136/ard.2009.110965.


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