Bugula neritina

Bugula neritina
The nudibranch Diaphorodoris papillata Portmann & Sandmeier, 1960 feeding on Bugula neritina (Linnaeus, 1758)
Scientific classification
Kingdom: Animalia
Phylum: Bryozoa
Class: Gymnolaemata
Order: Cheilostomata
Family: Bugulidae
Genus: Bugula
Species: B. neritina
Binomial name
Bugula neritina
(Linnaeus, 1758)[1]
Synonyms[2]

Sertularia neritina Linnaeus, 1758 (basionym)

Bugula neritina (commonly known as brown bryozoan or common bugula) is a cryptic species complex of sessile marine animal in the Bugula genus. [2]

It is invasive with a cosmopolitan distribution.[1]

Bugula neritina is of interest from a drug discovery perspective because it produces the bryostatins, a group of around twenty bioactive natural products. The bryostatins are under investigation as possible therapies for cancer[3][4] and Alzheimer's disease.[4][5]

Bugula neritina is also of interest in materials science, where it is used as a model organism in biofouling studies.[6]

References

  1. 1 2 "Bugula neritina (brown bryozoan)". CABI (organisation). 3 May 2013. Retrieved 14 March 2015.
  2. 1 2 Gordon, D. (2015). Bugula neritina (Linnaeus, 1758). In: Bock, P.; Gordon, D. (2015) World List of Bryozoa. Accessed through: World Register of Marine Species at http://www.marinespecies.org/aphia.php?p=taxdetails&id=111158 on 2015-09-02
  3. Singh R, Sharma M, Joshi P, Rawat DS (2008). "Clinical status of anti-cancer agents derived from marine sources". Anticancer Agents Med Chem 8 (6): 603–617. doi:10.2174/187152008785133074. PMID 18690825.
  4. 1 2 Ruan BF, Zhu HL (2012). "The chemistry and biology of the bryostatins: potential PKC inhibitors in clinical development". Curr Med Chem 19 (16): 2652–64. doi:10.2174/092986712800493020. PMID 22506770.
  5. "Bryostatin – Phase II clinical testing of a non-toxic PKC activator". Blanchette Rockefeller Neurosciences Institute (West Virginia University). Retrieved 14 March 2015.
  6. Yua X, Yana Y, Gua JD (2007). "Attachment of the biofouling bryozoan Bugula neritina larvae affected by inorganic and organic chemical cues". Int Biodeterior Biodegradation 60 (2): 81–89. doi:10.1016/j.ibiod.2006.12.003.


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