C15orf15

Ribosomal L24 domain containing 1
Identifiers
Symbols	RSL24D1 ; C15orf15; HRP-L30-iso; L30; RLP24; RPL24; RPL24L; TVAS3
External IDs	OMIM: 613262 HomoloGene: 9462 GeneCards: RSL24D1 Gene
Gene ontology Molecular function • structural constituent of ribosome • protein binding • poly(A) RNA binding Cellular component • nucleus • nucleolus • cytosolic large ribosomal subunit Biological process • ribosomal large subunit assembly • translation • assembly of large subunit precursor of preribosome Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	51187	225215
Ensembl	ENSG00000137876	ENSMUSG00000032215
UniProt	Q9UHA3	Q99L28
RefSeq (mRNA)	NM_016304	NM_198609
RefSeq (protein)	NP_057388	NP_941011
Location (UCSC)	Chr 15: 55.18 – 55.2 Mb	Chr 9: 73.11 – 73.12 Mb
PubMed search

Probable ribosome biogenesis protein RLP24 is a protein that in humans is encoded by the RSL24D1 gene.^[1][2][3]

This gene encodes a protein sharing a low level of sequence similarity with human ribosomal protein L24. Although this gene has been referred to as RPL24, L30, and 60S ribosomal protein L30 isolog in the sequence databases, it is distinct from the human genes officially named RPL24 (which itself has been referred to as ribosomal protein L30) and RPL30. The function of this gene is currently unknown. This gene utilizes alternative polyadenylation signals.^[3]

References

1. Saveanu C, Namane A, Gleizes PE, Lebreton A, Rousselle JC, Noaillac-Depeyre J, Gas N, Jacquier A, Fromont-Racine M (Jun 2003). "Sequential protein association with nascent 60S ribosomal particles". Mol Cell Biol 23 (13): 4449–60. doi:10.1128/MCB.23.13.4449-4460.2003. PMC 164837. PMID 12808088.
2. Saveanu C, Bienvenu D, Namane A, Gleizes PE, Gas N, Jacquier A, Fromont-Racine M (Nov 2001). "Nog2p, a putative GTPase associated with pre-60S subunits and required for late 60S maturation steps". EMBO J 20 (22): 6475–84. doi:10.1093/emboj/20.22.6475. PMC 125736. PMID 11707418.
3. "Entrez Gene: C15orf15 chromosome 15 open reading frame 15".

Further reading

• Scherl A, Couté Y, Déon C; et al. (2003). "Functional proteomic analysis of human nucleolus". Mol. Biol. Cell 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747.
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Andersen JS, Lam YW, Leung AK; et al. (2005). "Nucleolar proteome dynamics". Nature 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413.
• Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.