CC398

CC398 or MRSA CC398 is a new variant of MRSA that has emerged in animals and is found in intensively reared production animals (primarily pigs, but also cattle and poultry), where it can be transmitted to humans as LA-MRSA (livestock-associated MRSA). Though dangerous to humans, CC398 is often asymptomatic in food-producing animals.[1] In a single study conducted in Denmark, MRSA was shown to originate in livestock and spread to humans,[2] though the MRSA strain may have originated in humans and was transmitted to livestock.[3]

A 2011 study reported 47% of the meat and poultry sold in surveyed U.S. grocery stores was contaminated with S. aureus, and of those, 52% — or 24.4% of the total — were resistant to at least three classes of antibiotics. "Now we need to determine what this means in terms of risk to the consumer," said Dr. Keim, a co-author of the paper.[4] Some samples of commercially sold meat products in Japan were also found to harbor MRSA strains.[5]

An investigation of 100 pig-meat samples purchased from major UK retailers conducted by the Guardian in 2015 showed that some 10% of the samples were contaminated.[6]

See also

References

  1. ↑ Joint scientific report of ECDC, EFSA and EMEA on meticillin resistant Staphylococcus aureus (MRSA) in livestock, companion animals and food. European Food Safety Authority
  2. ↑ Harrison, Ewan M.; Paterson, Gavin K.; Holden, Matthew T.G.; Larsen, Jesper; Stegger, Marc; Larsen, Anders Rhod; Petersen, Andreas; Skov, Robert L.; et al. (2013). "Whole genome sequencing identifies zoonotic transmission of MRSA isolates with the novel mecA homologue mecC". EMBO Molecular Medicine 5 (4): 509–15. doi:10.1002/emmm.201202413. PMC 3628104. PMID 23526809.
  3. ↑ Tomasz, Alexander (April 2013). "The use of whole genome sequencing to solve an epidemiological puzzle". EMBO Molecular Medicine 5 (4): 486–487. doi:10.1002/emmm.201302622.
  4. ↑ "US meat and poultry is widely contaminated with drug-resistant Staph bacteria, study finds". ScienceDaily.
  5. ↑ Ogata K, Narimatsu H, Suzuki M, Higuchi W, Yamamoto T, Taniguchi H (2012-02-03). "Commercially distributed meat as a potential vehicle for community-acquired methicillin-resistant Staphylococcus aureus". Applied and environmental microbiology 78 (8): 2797–802. doi:10.1128/AEM.07470-11. PMC 3318828. PMID 22307310.
  6. ↑ Harvey, Fiona; Wasley, Andrew; Stuart, Caz; Carson, Mary; O'Kane, Maggie; Mann, Ben; Baqué, Irene; Lukic, Dee; Parkar, Yusuf (18 June 2015). "The pig superbug and the baby – video". The Guardian.
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