CD300C

CD300c molecule
Identifiers
Symbols	CD300C ; CLM-6; CMRF-35; CMRF-35A; CMRF35; CMRF35-A1; CMRF35A; CMRF35A1; IGSF16; LIR
External IDs	OMIM: 606786 MGI: 3032626 HomoloGene: 74580 GeneCards: CD300C Gene
Gene ontology Molecular function • transmembrane signaling receptor activity Cellular component • integral component of plasma membrane Biological process • immune system process • cellular defense response • signal transduction Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	10871	140497
Ensembl	ENSG00000167850	ENSMUSG00000044811
UniProt	Q08708	Q7TSN2
RefSeq (mRNA)	NM_006678	NM_134158
RefSeq (protein)	NP_006669	NP_598919
Location (UCSC)	Chr 17: 74.54 – 74.55 Mb	Chr 11: 115 – 115 Mb
PubMed search

CMRF35-like molecule 6 (CLM-6) also known as CD300 antigen-like family member C (CD300c) is a protein that in humans is encoded by the CD300C gene.^[1][2][3]

The CMRF35 antigen, which was identified by reactivity with a monoclonal antibody, is present on monocytes, neutrophils, and some T and B lymphocytes.^[3]

References

1. Jackson DG, Hart DN, Starling G, Bell JI (Jun 1992). "Molecular cloning of a novel member of the immunoglobulin gene superfamily homologous to the polymeric immunoglobulin receptor". Eur J Immunol 22 (5): 1157–63. doi:10.1002/eji.1830220508. PMID 1349532.
2. Clark GJ, Green BJ, Hart DN (Aug 2000). "The CMRF-35H gene structure predicts for an independently expressed member of an ITIM/ITAM pair of molecules localized to human chromosome 17". Tissue Antigens 55 (2): 101–9. doi:10.1034/j.1399-0039.2000.550201.x. PMID 10746781.
3. "Entrez Gene: CD300C CD300c molecule".

Further reading

• Clark GJ, Fitzpatrick S, Kuo B, Modra C, Jamriska L, Hart DN (2002). "CMRF-35A, CMRF-35H: potential new CD". J. Biol. Regul. Homeost. Agents 16 (3): 233–5. PMID 12456026.
• Cannon JP, Haire RN, Litman GW (December 2002). "Identification of diversified genes that contain immunoglobulin-like variable regions in a protochordate". Nat. Immunol. 3 (12): 1200–7. doi:10.1038/ni849. PMID 12415263.
• Clark GJ, Cooper B, Fitzpatrick S, Green BJ, Hart DN (May 2001). "The gene encoding the immunoregulatory signaling molecule CMRF-35A localized to human chromosome 17 in close proximity to other members of the CMRF-35 family". Tissue Antigens 57 (5): 415–23. doi:10.1034/j.1399-0039.2001.057005415.x. PMID 11556966.