CENTG3

ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 3IHW​
Identifiers
Symbols	AGAP3 ; AGAP-3; CENTG3; CRAG; MRIP-1; cnt-g3
External IDs	MGI: 2183446 HomoloGene: 23742 GeneCards: AGAP3 Gene
Gene ontology Molecular function • GTPase activator activity • GTP binding • metal ion binding Cellular component • cytoplasm • membrane Biological process • small GTPase mediated signal transduction • positive regulation of GTPase activity Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	116988	213990
Ensembl	ENSG00000133612	ENSMUSG00000023353
UniProt	Q96P47	F8VQE9
RefSeq (mRNA)	NM_001042535	NM_001256431
RefSeq (protein)	NP_001036000	NP_001243360
Location (UCSC)	Chr 7: 151.09 – 151.14 Mb	Chr 5: 24.45 – 24.5 Mb
PubMed search

Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 is an enzyme that in humans is encoded by the AGAP3 gene.^[1]

References

1. "Entrez Gene: CENTG3 centaurin, gamma 3".

Further reading

• Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–1292. doi:10.1038/nbt1240. PMID 16964243.
• Qin Q, Inatome R, Hotta A, et al. (2006). "A novel GTPase, CRAG, mediates promyelocytic leukemia protein-associated nuclear body formation and degradation of expanded polyglutamine protein". J. Cell Biol. 172 (4): 497–504. doi:10.1083/jcb.200505079. PMC 2063670. PMID 16461359.
• Meurer S, Pioch S, Wagner K, et al. (2005). "AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase". J. Biol. Chem. 279 (47): 49346–49354. doi:10.1074/jbc.M410565200. PMID 15381706.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039.
• Surks HK, Richards CT, Mendelsohn ME (2004). "Myosin phosphatase-Rho interacting protein. A new member of the myosin phosphatase complex that directly binds RhoA". J. Biol. Chem. 278 (51): 51484–51493. doi:10.1074/jbc.M305622200. PMID 14506264.
• Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science 300 (5620): 767–772. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
• Xia C, Ma W, Stafford LJ, et al. (2003). "GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins". Mol. Cell. Biol. 23 (7): 2476–2488. doi:10.1128/MCB.23.7.2476-2488.2003. PMC 150724. PMID 12640130.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.