CFHR3
| Complement factor H-related 3 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbols | CFHR3 ; CFHL3; DOWN16; FHR-3; FHR3; HLF4 | ||||||||
| External IDs | OMIM: 605336 MGI: 3647418 HomoloGene: 137347 GeneCards: CFHR3 Gene | ||||||||
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| RNA expression pattern | |||||||||
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| More reference expression data | |||||||||
| Orthologs | |||||||||
| Species | Human | Mouse | |||||||
| Entrez | 10878 | 624286 | |||||||
| Ensembl | ENSG00000116785 | n/a | |||||||
| UniProt | Q02985 | n/a | |||||||
| RefSeq (mRNA) | NM_001166624 | n/a | |||||||
| RefSeq (protein) | NP_001160096 | n/a | |||||||
| Location (UCSC) |
Chr 1: 196.77 – 196.8 Mb | n/a | |||||||
| PubMed search | |||||||||
Complement factor H-related protein 3 is a protein that in humans is encoded by the CFHR3 gene.[1][2][3]
References
- ↑ Skerka C, Kuhn S, Gunther K, Lingelbach K, Zipfel PF (Mar 1993). "A novel short consensus repeat-containing molecule is related to human complement factor H". J Biol Chem 268 (4): 2904–8. PMID 8428964.
- ↑ Diaz-Guillen MA, Rodriguez de Cordoba S, Heine-Suner D (Jul 1999). "A radiation hybrid map of complement factor H and factor H-related genes". Immunogenetics 49 (6): 549–52. doi:10.1007/s002510050534. PMID 10380701.
- ↑ "Entrez Gene: CFHR3 complement factor H-related 3".
Further reading
- Zipfel PF, Skerka C (1994). "Complement factor H and related proteins: an expanding family of complement-regulatory proteins?". Immunol. Today 15 (3): 121–6. doi:10.1016/0167-5699(94)90155-4. PMID 8172644.
- Hellwage J, Jokiranta TS, Koistinen V; et al. (2000). "Functional properties of complement factor H-related proteins FHR-3 and FHR-4: binding to the C3d region of C3b and differential regulation by heparin.". FEBS Lett. 462 (3): 345–52. doi:10.1016/S0014-5793(99)01554-9. PMID 10622723.
- Male DA, Ormsby RJ, Ranganathan S; et al. (2000). "Complement factor H: sequence analysis of 221 kb of human genomic DNA containing the entire fH, fHR-1 and fHR-3 genes.". Mol. Immunol. 37 (1-2): 41–52. doi:10.1016/S0161-5890(00)00024-9. PMID 10781834.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Gregory SG, Barlow KF, McLay KE; et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
- Zipfel PF, Edey M, Heinen S; et al. (2007). "Deletion of complement factor H-related genes CFHR1 and CFHR3 is associated with atypical hemolytic uremic syndrome.". PLoS Genet. 3 (3): e41. doi:10.1371/journal.pgen.0030041. PMC 1828695. PMID 17367211.
External links
- GeneReviews/NCBI/NIH/UW entry on Atypical Hemolytic-Uremic Syndrome
- OMIM entries on Atypical Hemolytic-Uremic Syndrome
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