CHST14

Carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
Identifiers
Symbols	CHST14 ; ATCS; D4ST1; EDSMC1; HNK1ST
External IDs	OMIM: 608429 MGI: 1919386 HomoloGene: 12443 GeneCards: CHST14 Gene
EC number	2.8.2.35
Gene ontology Molecular function • N-acetylgalactosamine 4-O-sulfotransferase activity • phosphate ion binding Cellular component • Golgi membrane • integral component of membrane • extracellular exosome Biological process • carbohydrate metabolic process • carbohydrate biosynthetic process • glycosaminoglycan metabolic process • chondroitin sulfate metabolic process • dermatan sulfate biosynthetic process • small molecule metabolic process • dermatan sulfate proteoglycan metabolic process Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	113189	72136
Ensembl	ENSG00000169105	ENSMUSG00000074916
UniProt	Q8NCH0	Q80V53
RefSeq (mRNA)	NM_130468	NM_028117
RefSeq (protein)	NP_569735	NP_082393
Location (UCSC)	Chr 15: 40.47 – 40.47 Mb	Chr 2: 118.93 – 118.93 Mb
PubMed search

Carbohydrate sulfotransferase 14 is an enzyme that in humans is encoded by the CHST14 gene.^[1][2]

References

1. Evers MR, Xia G, Kang HG, Schachner M, Baenziger JU (Sep 2001). "Molecular cloning and characterization of a dermatan-specific N-acetylgalactosamine 4-O-sulfotransferase". J Biol Chem 276 (39): 36344–53. doi:10.1074/jbc.M105848200. PMID 11470797.
2. "Entrez Gene: D4ST1 dermatan 4 sulfotransferase 1".

Further reading

• Otsuki T, Ota T, Nishikawa T; et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Clark HF, Gurney AL, Abaya E; et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Mikami T, Mizumoto S, Kago N; et al. (2003). "Specificities of three distinct human chondroitin/dermatan N-acetylgalactosamine 4-O-sulfotransferases demonstrated using partially desulfated dermatan sulfate as an acceptor: implication of differential roles in dermatan sulfate biosynthesis.". J. Biol. Chem. 278 (38): 36115–27. doi:10.1074/jbc.M306044200. PMID 12847091.
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.