CIAO1

Cytosolic iron-sulfur assembly component 1
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 3FM0​
Identifiers
Symbols	CIAO1 ; CIA1; WDR39
External IDs	OMIM: 604333 MGI: 1346998 HomoloGene: 55850 GeneCards: CIAO1 Gene
Gene ontology Molecular function • protein binding Cellular component • MMXD complex • CIA complex Biological process • regulation of transcription from RNA polymerase II promoter • chromosome segregation • positive regulation of cell proliferation • iron-sulfur cluster assembly • small molecule metabolic process Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	9391	26371
Ensembl	ENSG00000144021	ENSMUSG00000003662
UniProt	O76071	Q99KN2
RefSeq (mRNA)	NM_004804	NM_025296
RefSeq (protein)	NP_004795	NP_079572
Location (UCSC)	Chr 2: 96.27 – 96.27 Mb	Chr 2: 127.24 – 127.25 Mb
PubMed search

Probable cytosolic iron-sulfur protein assembly protein CIAO1 is a protein that in humans is encoded by the CIAO1 gene.^[1][2][3]

References

1. Johnstone RW, Wang J, Tommerup N, Vissing H, Roberts T, Shi Y (Jun 1998). "Ciao 1 is a novel WD40 protein that interacts with the tumor suppressor protein WT1". J Biol Chem 273 (18): 10880–7. doi:10.1074/jbc.273.18.10880. PMID 9556563.
2. Loftus BJ, Kim UJ, Sneddon VP, Kalush F, Brandon R, Fuhrmann J, Mason T, Crosby ML, Barnstead M, Cronin L, Deslattes Mays A, Cao Y, Xu RX, Kang HL, Mitchell S, Eichler EE, Harris PC, Venter JC, Adams MD (Nov 1999). "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q". Genomics 60 (3): 295–308. doi:10.1006/geno.1999.5927. PMID 10493829.
3. "Entrez Gene: CIAO1 cytosolic iron-sulfur protein assembly 1 homolog (S. cerevisiae)".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
• Higa LA, Wu M, Ye T; et al. (2006). "CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation.". Nat. Cell Biol. 8 (11): 1277–83. doi:10.1038/ncb1490. PMID 17041588.
• Ewing RM, Chu P, Elisma F; et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.