CLDN20

Claudin 20
Identifiers
Symbol	CLDN20
External IDs	MGI: 3646757 HomoloGene: 47972 GeneCards: CLDN20 Gene
Gene ontology Molecular function • structural molecule activity • identical protein binding Cellular component • plasma membrane • bicellular tight junction • integral component of membrane Biological process • calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules • cell junction assembly • cell-cell junction organization • bicellular tight junction assembly Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	49861	621628
Ensembl	ENSG00000171217	ENSMUSG00000091530
UniProt	P56880	G5E8X0
RefSeq (mRNA)	NM_001001346	NM_001101560
RefSeq (protein)	NP_001001346	NP_001095030
Location (UCSC)	Chr 6: 155.26 – 155.28 Mb	Chr 17: 3.53 – 3.53 Mb
PubMed search

Claudin-20 is a protein that in humans is encoded by the CLDN20 gene.^[1][2] It belongs to the group of claudins.

References

1. Hewitt KJ, Agarwal R, Morin PJ (Aug 2006). "The claudin gene family: expression in normal and neoplastic tissues". BMC Cancer 6: 186. doi:10.1186/1471-2407-6-186. PMC 1538620. PMID 16836752.
2. "Entrez Gene: CLDN20 claudin 20".

Further reading

• Kniesel U, Wolburg H (2000). "Tight junctions of the blood–brain barrier". Cell. Mol. Neurobiol. 20 (1): 57–76. doi:10.1023/A:1006995910836. PMID 10690502.
• Heiskala M, Peterson PA, Yang Y (2001). "The roles of claudin superfamily proteins in paracellular transport". Traffic 2 (2): 93–8. doi:10.1034/j.1600-0854.2001.020203.x. PMID 11247307.
• Tsukita S, Furuse M, Itoh M (2001). "Multifunctional strands in tight junctions". Nat. Rev. Mol. Cell Biol. 2 (4): 285–93. doi:10.1038/35067088. PMID 11283726.
• Tsukita S, Furuse M (2003). "Claudin-based barrier in simple and stratified cellular sheets". Curr. Opin. Cell Biol. 14 (5): 531–6. doi:10.1016/S0955-0674(02)00362-9. PMID 12231346.
• González-Mariscal L, Betanzos A, Nava P, Jaramillo BE (2003). "Tight junction proteins". Prog. Biophys. Mol. Biol. 81 (1): 1–44. doi:10.1016/S0079-6107(02)00037-8. PMID 12475568.
• Berg M, Geisel A, Necheles H (1975). "The influence of carbenoxolone on steroid-induced ulcer and mucus secretion in the rat". The American journal of digestive diseases 20 (2): 134–7. doi:10.1007/BF01072339. PMID 1124737.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Liu F, Koval M, Ranganathan S, Fanayan S, Hancock WS, Lundberg EK, Beavis RC, Lane L, Duek P, McQuade L, Kelleher NL, Baker MS (2015). "A systems proteomics view of the endogenous human claudin protein family". J Proteome Res. doi:10.1021/acs.jproteome.5b00769. PMID 26680015.