Contactin 6
| Contactin 6 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||
| Symbols | CNTN6 ; NB3 | ||||||||||
| External IDs | OMIM: 607220 HomoloGene: 8702 GeneCards: CNTN6 Gene | ||||||||||
| |||||||||||
| Orthologs | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | 27255 | 53870 | |||||||||
| Ensembl | ENSG00000134115 | ENSMUSG00000030092 | |||||||||
| UniProt | Q9UQ52 | Q9JMB8 | |||||||||
| RefSeq (mRNA) | NM_001289080 | NM_017383 | |||||||||
| RefSeq (protein) | NP_001276009 | NP_059079 | |||||||||
| Location (UCSC) |
Chr 3: 1.09 – 1.4 Mb |
Chr 6: 104.49 – 104.86 Mb | |||||||||
| PubMed search | |||||||||||
Contactin 6 is a protein in humans that is encoded by the CNTN6 gene. [1]
The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. [provided by RefSeq, Jul 2008]. ##RefSeq-Attributes-START## Transcript_exon_combination_evidence :: AB003592.1 [ECO:0000332] ##RefSeq-Attributes-END##
References
- ↑ "Entrez Gene: Contactin 6". Retrieved 2012-08-09.
Further reading
- Manderson, E. N.; Birch, A. H.; Shen, Z.; Mes-Masson, A. M.; Provencher, D.; Tonin, P. N. (2009). "Molecular Genetic Analysis of a Cell Adhesion Molecule with Homology to L1CAM, Contactin 6, and Contactin 4 Candidate Chromosome 3p26pter Tumor Suppressor Genes in Ovarian Cancer". International Journal of Gynecological Cancer 19 (4): 513–525. doi:10.1111/IGC.0b013e3181a3cd38. PMID 19509545.
- Wang, K.; Zhang, H.; Bloss, C. S.; Duvvuri, V.; Kaye, W.; Schork, N. J.; Berrettini, W.; Hakonarson, H. (2010). "A genome-wide association study on common SNPs and rare CNVs in anorexia nervosa". Molecular Psychiatry 16 (9): 949–959. doi:10.1038/mp.2010.107. PMID 21079607.
- Barber, M. J.; Mangravite, L. M.; Hyde, C. L.; Chasman, D. I.; Smith, J. D.; McCarty, C. A.; Li, X.; Wilke, R. A.; Rieder, M. J.; Williams, P. T.; Ridker, P. M.; Chatterjee, A.; Rotter, J. I.; Nickerson, D. A.; Stephens, M.; Krauss, R. M. (2010). Zanger, Ulrich, ed. "Genome-Wide Association of Lipid-Lowering Response to Statins in Combined Study Populations". PLoS ONE 5 (3): e9763. doi:10.1371/journal.pone.0009763. PMC 2842298. PMID 20339536.
- Kamei, Y.; Tsutsumi, O.; Taketani, Y.; Watanabe, K. (1998). "CDNA cloning and chromosomal localization of neural adhesion molecule NB-3 in human". Journal of Neuroscience Research 51 (3): 275–283. doi:10.1002/(SICI)1097-4547(19980201)51:3<275::AID-JNR1>3.0.CO;2-D. PMID 9486763.
- Walsh, F. S.; Doherty, P. (1991). "Glycosylphosphatidylinositol anchored recognition molecules that function in axonal fasciculation, growth and guidance in the nervous system". Cell biology international reports 15 (11): 1151–1166. doi:10.1016/0309-1651(91)90061-M. PMID 1838307.
- Nie, D. -Y.; Zhou, Z. H.; Ang, B. T.; Teng, F. Y.; Xu, G.; Xiang, T.; Wang, C. Y.; Zeng, L.; Takeda, Y.; Xu, T. L.; Ng, Y. K.; Faivre-Sarrailh, C.; Popko, B.; Ling, E. A.; Schachner, M.; Watanabe, K.; Pallen, C. J.; Tang, B. L.; Xiao, Z. C. (2003). "Nogo-A at CNS paranodes is a ligand of Caspr: Possible regulation of K+ channel localization". The EMBO Journal 22 (21): 5666–5678. doi:10.1093/emboj/cdg570. PMC 275427. PMID 14592966.
- Saus, E.; Brunet, A.; Armengol, L. S.; Alonso, P.; Crespo, J. M.; Fernández-Aranda, F.; Guitart, M.; Martín-Santos, R. O.; Menchón, J. M.; Navinés, R.; Soria, V.; Torrens, M.; Urretavizcaya, M.; Vallès, V.; Gratacòs, M. N.; Estivill, X. (2010). "Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients". Journal of Psychiatric Research 44 (14): 971–978. doi:10.1016/j.jpsychires.2010.03.007. PMID 20398908.
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