COQ2

Coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
Identifiers
Symbols COQ2 ; CL640; COQ10D1; MSA1; PHB:PPT
External IDs OMIM: 609825 MGI: 1919133 HomoloGene: 69192 GeneCards: COQ2 Gene
EC number 2.5.1.39
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 27235 71883
Ensembl ENSG00000173085 ENSMUSG00000029319
UniProt Q96H96 Q66JT7
RefSeq (mRNA) NM_015697 NM_027978
RefSeq (protein) NP_056512 NP_082254
Location (UCSC) Chr 4:
83.26 – 83.28 Mb
Chr 5:
100.65 – 100.68 Mb
PubMed search

Para-hydroxybenzoate--polyprenyltransferase, mitochondrial is an enzyme that in humans is encoded by the COQ2 gene.[1][2]

CoQ (ubiquinone) serves as a redox carrier in the mitochondrial respiratory chain and is a lipid-soluble antioxidant. COQ2, or parahydroxybenzoate-polyprenyltransferase (EC 2.5.1.39), catalyzes one of the final reactions in the biosynthesis of CoQ, the prenylation of parahydroxybenzoate with an all-trans polyprenyl group (Forsgren et al., 2004).[supplied by OMIM][2]

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Further reading


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