Calfactant
| Clinical data | |
|---|---|
| Trade names | Infasurf |
| Pregnancy category |
|
| Legal status |
|
| Identifiers | |
| ATC code | None |
| ChemSpider | none |
| UNII |
Q4K217VGA9  |
| ChEMBL |
CHEMBL1201447  |
| (what is this?) (verify) | |
Calfactant, also known as Infasurf,[1] is an intratracheal suspension derived from the natural surfactant in calf lungs. It is used in premature infants with lung surfactant deficiency that causes infant respiratory distress syndrome (IRDS).[2]
Mechanism of action
Lung surfactant is essential for effective ventilation as it modifies alveolar surface tension.[3] IRDS is caused by a lung surfactant deficiency. Calfactant serves as a substitute for the natural surfactant.[2]
References
- ↑ http://www.infasurf.com/home
- 1 2 Drugs.com: Calfactant
- ↑ Schurch, S.; Lee, M.; Gehr, P. (1992). "Pulmonary surfactant: Surface properties and function of alveolar and airway surfactant". Pure and Applied Chemistry 64 (11): 1745. doi:10.1351/pac199264111745. PMID 11369545.
This article is issued from Wikipedia - version of the Monday, December 28, 2015. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.